Publications

Taking Lyophilization for a Spin

Continuous freeze-drying of mRNA LNPs enables storage at higher temperatures

The pharmaceutical industry is increasingly recognizing the need to speed up and improve the lyophilization process, specifically for mRNA LNP-based vaccines and in the event of any future pandemic preparedness requirements. Thus, Thomas De Beer, Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium, helped pioneer a spin freeze drying stabilization technique that could bring about an end to frozen mRNA vaccine storage – with the additional benefit of moving away from batch towards Continuous Lyophilization with a New Technique: Spin Freeze Drying continuous processing and manufacturing.

Click here to read the article.

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by Alain Segers

Continuous freeze-drying of mRNA LNPs enables storage at higher temperatures

Publications

Continuous freeze-drying of mRNA LNPs enables storage at higher temperatures

Research at Ghent University, in collaboration with The University of British Columbia, has shown that continuous freeze-drying of mRNA LNPs enables long-term storage at higher temperatures for months without losing their transfection properties.

The full article can be read and downloaded here

Please contact us via info@rheavita.com if you wish to learn more about how continuous freeze-drying enables the stabilization of your mRNA therapy for distribution and storage.

For formulation development, the freeze-drying process development, and production, we can be your partner in getting your therapy fast to the market with the highest quality while avoiding cold chain logistics.

For the most up to date news, please follow us on LinkedIn via the link below

by Alain Segers

New poster publications available

Publications

2 new poster publications are available

Implementing PAT for real-time product monitoring and control during continuous freeze-drying can be read and downloaded here

Avoiding cold chain logistics can be read and downloaded here

For the most up to date news, please follow us on LinkedIn via the link below

by Alain Segers

Condensorless freeze-drying

Publications

Presented poster on freeze-drying as a gene therapy stabilizer

Easier in maintenance, less complicated CIP/SIP procedures and shorter change over times.

Condensorless freeze-drying has a lot of advantages. RheaVita’s continuous freeze-drying technology combined with Edwards Vacuum vacuum pumps makes it possible.

Read all about it in this white paper which you can read and download for free this page on our website.

Do you have questions? Don’t hesitate to reach out to us via info@rheavita.com

For the most up to date news, please follow us on LinkedIn via the link below

by Alain Segers