RheaVita is currently developing the first continuous freeze-drying system allowing GMP production, which is expected to be ready mid 2023. The 3D design engineering was finished at the end of 2020. First visual impressions and further technical information will be provided soon. Currently, the detail engineering phase is being finalized (together with the development of a digital twin of the technology) and will followed by the assembly of the first GMP continuous freeze-drying line. This GMP-compliant Continuous Freeze-Drying Production Line allowing aseptic processing and integration in the entire manufacturing chain of the sterile product will be installed at the RheaVita facilities and will be available for testing and the production of products.

Following features will be implemented:

• Aseptic processing
• Integrated PAT
• Modular approach
• Proven technology
• Model-based design
• High flexibility/production efficiency: rapid change-over, short CIP/SIP times